TESTOSTERONE CYPIONATE 200

Strength: 250 mg/ml
Molecular Formula: C27H40O3,
Molecular Weight: 412.6047 g/mol
Active Ingredient: Testosterone cypionate
CAS number: 58-20-8
Dosage Form: Injectable, oil base sterile solution
Route: Injection
Market Status: Prescription

Chemical Structure: Testosterone cypionate

Categories:
Description
Mechanisms of Action
Contraindications & Precautions
Interactions
Adverse Reactions / Side Effects
Pregnancy & Breastfeeding
Storage
Description

Testosterone cypionate 200 mg/mL is an injectable form of testosterone used primarily to treat low testosterone levels in adult males, a condition known as hypogonadism. Here are some key details:

Description

  • Form: Injectable solution
  • Strength: 200 mg/mL
  • Brand Name: Depo-Testosterone
  • Generic Name: Testosterone cypionate

Uses

  • Primary Use: Treats symptoms of low testosterone in males, such as mood changes, difficulty concentrating, erectile dysfunction, and low sex drive.
  • Administration: Injected into the muscle, typically in the buttock. It can be self-administered at home after proper training by a healthcare provider
Mechanisms of Action

Testosterone cypionate 200 mg/mL works by supplementing or replacing testosterone in the body. Here’s a detailed look at its mechanism of action:

Mechanism of Action

  • Testosterone Replacement: Testosterone cypionate is a synthetic version of the naturally occurring male hormone testosterone. When injected, it is absorbed into the bloodstream and converted into active testosterone.
  • Androgen Receptor Activation: Testosterone binds to androgen receptors in various tissues throughout the body. This binding activates the receptors, leading to the expression of specific genes that regulate the development and maintenance of male characteristics.
  • Protein Synthesis: It promotes protein synthesis, which is essential for muscle growth and repair. This is why it is often used to treat conditions that cause muscle wasting.
  • Red Blood Cell Production: Testosterone stimulates the production of red blood cells by increasing erythropoiesis in the bone marrow. This can improve oxygen delivery to tissues and enhance physical performance.
Contraindications & Precautions

Contraindications

Testosterone cypionate 200 mg/mL should not be used in the following conditions:

  • Hypersensitivity: Known hypersensitivity to testosterone cypionate or any of its components.
  • Breast or Prostate Cancer: Men with carcinoma of the breast or known or suspected carcinoma of the prostate.
  • Pregnancy: Women who are pregnant or may become pregnant, as testosterone can cause fetal harm.
  • Severe Cardiac, Hepatic, or Renal Disease: Individuals with severe heart, liver, or kidney conditions.

Precautions

  • Heart and Blood Vessel Health: Increased risk of heart attack, stroke, and blood clots (e.g., deep vein thrombosis, pulmonary embolism).
  • Prostate Health: May increase the risk of prostate cancer, especially in older males.
  • Liver Health: Potential for serious liver problems, including liver cancer.
  • Fluid Retention: Can cause edema (fluid and sodium retention), leading to swelling of the fingers, hands, feet, or lower legs.
  • Cholesterol Levels: May cause changes in cholesterol and fat levels in the blood.
  • Sleep Apnea: Can worsen sleep apnea in some individuals.
  • Sperm Production: May decrease sperm production and affect fertility.
  • Gynecomastia: Can cause swelling of the breasts and breast pain in some patients.
  • Hypercalcemia: High calcium levels in the blood ma

    in

    y occur.

Monitorg

Regular monitoring by a healthcare provider is essential to check for unwanted effects and ensure the medication is working properly. Blood and urine tests may be needed to monitor for side effects.

Liver problems warning: Using high doses of this drug for a long period of time can increase your risk of liver problems. These problems include liver cancer and hepatitis. These are serious conditions that can be life-threatening.
Blood clots warning: This drug may raise your risk of developing blood clots in your lungs or the deep veins of your legs.

Before using testosterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as sesame oil), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: cancer (such as breast cancer in men, prostate cancer), blood clots (such as in the leg, lungs), heart disease (such as heart failure, chest pain, heart attack), stroke, liver problems, kidney problems, high cholesterol, high blood pressure, enlarged prostate, sleep apnea, diabetes.

If you have diabetes, this product may lower your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of low blood sugar, such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Children may be more sensitive to the side effects of this drug. In children, it may affect bone growth. Check your child's height periodically.

Older adults may be more sensitive to the side effects of this drug, especially prostate/liver problems, swelling of arms/legs.

This medication can affect fertility in males. Ask your doctor for more details.

This medication must not be used during pregnancy. It may harm an unborn baby. Discuss the use of reliable forms of birth control (such as condoms, birth control pills) with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away.

It is unknown if this drug passes into breast milk. It may affect milk production and it may harm a nursing infant. Breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Interactions

Some medicines can affect how testosterone works. Tell your doctor if you are using any of the following: OxyphenbutazoneBlood thinner (including warfarin)Insulin or oral diabetes medicineSteroid medicine (including dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone)

Tell your doctor if you have kidney disease, liver disease, heart disease, diabetes, an enlarged prostate, high cholesterol, lung disease, sleep apnea, or a history of heart attack.

This medicine may cause the following problems:Serious lung reaction called pulmonary oil embolism (may be life-threatening)Increased risk of prostate cancerBlood clot in your leg or lungSlow growth in childrenLiver problemsPossible increased risk of heart attack or stroke

This medicine can cause women to develop male characteristics, such as a deep voice and facial hair growth. It can also cause a lower sperm count or swollen breasts in men. Talk to your doctor if you are concerned about this.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Adverse Reactions / Side Effects

Testosterone cypionate 200 mg/mL, an injectable form of testosterone, can have several side effects. Here are some common and serious adverse reactions:

Common Side Effects

  • Injection site reactions: Pain, redness, or swelling at the injection site.
  • Acne and oily skin.
  • Hair loss.
  • Headache.
  • Nausea and vomiting.
  • Changes in sexual interest: Either increased or decreased.
  • Gynecomastia: Enlargement of breast tissue in males.
  • More frequent erections.

Serious Side Effects

  • Cardiovascular issues: Increased risk of heart attack, stroke, and blood clots.
  • Liver problems: Signs include yellowing of the skin or eyes (jaundice) and abdominal pain.
  • Mental/mood changes: Depression, anxiety, or aggressive behavior.
  • Respiratory issues: Shortness of breath or rapid breathing.
  • Severe allergic reactions: Rash, itching/swelling, severe dizziness, and trouble breathing.

Special Considerations

  • Pregnancy and breastfeeding: This medication should not be used during pregnancy or while breastfeeding due to potential harm to the baby.
  • Prostate issues: Men with prostate cancer or an enlarged prostate should use this medication with caution.

If you experience any severe side effects or symptoms, it’s important to seek medical attention immediately. Always discuss any concerns or side effects with your healthcare provider to ensure safe and effective use of the medication.

Pregnancy & Breastfeeding

Testosterone Cypionate 200 is not recommended for use during pregnancy or breastfeeding due to potential risks and adverse effects. Here are some key points:

Pregnancy

  • Contraindicated: Testosterone Cypionate should not be used by pregnant individuals as it can cause harm to the unborn baby, including birth defects.
  • Precautions: If pregnancy occurs while using this medication, it is crucial to inform your healthcare provider immediately.

Breastfeeding

  • Not Recommended: This medication is not advised for breastfeeding individuals. Testosterone can pass into breast milk and may affect milk production and potentially harm the nursing infant.
  • Alternatives: Consult your healthcare provider for safer alternatives if you are breastfeeding.
Storage

Testosterone cypionate 200 mg/mL should be stored at a controlled room temperature of 20° to 25°C (68° to 77°F). It’s important to protect it from light to maintain its stability and effectiveness.

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