Boldenone undecylenate is a veterinary drug used primarily in horses, dogs, and livestock to promote muscle growth and improve physical performance. It exerts its effects by binding to androgen receptors, triggering molecular events that regulate gene expression. This leads to increased protein synthesis and muscle growth. Boldenone undecylenate also has masculinizing effects on male sexual characteristics. Common side effects include changes in behavior, increased aggression, masculinization in female animals, and effects on the reproductive system. Its use as a veterinary drug is supervised by licensed professionals, but it is not approved in all countries and is illegal for human use.

Boldenone Undecylenate works by increasing nitrogen retention and protein synthesis in the muscles, essential processes for muscle growth and recovery. It also enhances red blood cell production, improving oxygen delivery to the muscles, thereby boosting endurance and performance. Boldenone has a moderate androgenic effect, which helps in muscle preservation and overall physical enhancement without excessive water retention.

Boldenone undecylenate, commonly known as Equipoise, is an anabolic steroid and androgen. Its mechanisms of action include:

Androgen Receptor Agonism: Boldenone binds to androgen receptors in the body, which are the biological targets of androgens like testosterone. This binding regulates gene transcription, leading to various anabolic effects12.
Increased Nitrogen Retention: It enhances nitrogen retention in muscles, which is crucial for muscle growth and repair3.
Protein Synthesis: Boldenone stimulates protein synthesis, which helps in muscle building and recovery3.
Erythropoietin Stimulation: It stimulates the release of erythropoietin in the kidneys, which increases red blood cell production. This can improve oxygen delivery to muscles, enhancing endurance and performance4.
Inhibition of Muscle Wasting Hormones: Boldenone inhibits catabolic hormones that cause muscle breakdown, helping to preserve muscle mass.

Boldenone undecylenate 200mg, like other anabolic steroids, has specific contraindications and precautions to consider:

Contraindications

1. Hypersensitivity: Known hypersensitivity to boldenone or any of its components.
2. Carcinoma: Males with carcinoma of the breast or known/suspected carcinoma of the prostate.
3. Pregnancy: Women who are or may become pregnant.
4. Severe Health Conditions: Patients with serious cardiac, hepatic, or renal disease

Precautions

1. Prostatic Hypertrophy: Patients with benign prostatic hypertrophy may develop acute urethral obstruction.
2. Priapism: Excessive sexual stimulation or priapism may occur.
3. Oligospermia: Prolonged administration or excessive dosage may lead to oligospermia.
4. Monitoring: Regular monitoring of hemoglobin, hematocrit levels, and serum cholesterol is recommended during long-term therapy.
5. Drug Interactions: Androgens may increase sensitivity to oral anticoagulants and affect insulin requirements in diabetic patients

Boldenone undecylenate 200mg can interact with various medications and substances. Here are some key interactions to be aware of:

Drug Interactions

1. Anticoagulants: Boldenone may enhance the effects of oral anticoagulants, increasing the risk of bleeding.
2. Insulin and Oral Hypoglycemics: It can affect blood glucose levels, potentially altering the requirements for insulin or oral hypoglycemic agents in diabetic patients.
3. Corticosteroids: Concurrent use with corticosteroids may increase the risk of edema.
4. Hepatotoxic Drugs: Combining boldenone with other hepatotoxic drugs can increase the risk of liver damage.

Substance Interactions

1. Alcohol: Alcohol consumption can exacerbate the hepatotoxic effects of boldenone.
2. Herbal Supplements: Some herbal supplements, especially those affecting hormone levels, may interact with boldenone.

Monitoring and Precautions

• Regular Monitoring: Regular monitoring of liver function, blood glucose levels, and coagulation parameters is recommended during the use of boldenone.
• Consult Healthcare Provider: Always consult with a healthcare provider before starting or stopping any medication while using boldenone.

The most common side effects of boldenone undecylenate include changes in behavior and increased aggression. In horses, this may manifest as restlessness, irritability, and increased desire to fight. In dogs, boldenone undecylenate may cause agitation, hyperactivity, and territorial aggression. These behavioral changes are likely due to the drug's impact on the central nervous system. Another common side effect of boldenone undecylenate is masculinization in female animals. This can result in physical changes such as the development of male-typical genitalia and secondary sexual characteristics. In severe cases, this may lead to infertility in female animals. Boldenone undecylenate can also affect the reproductive system of animals. It may cause changes in the normal menstrual cycle or lead to a complete absence of menstruation (pseudopregnancy). In males, boldenone undecylenate can stimulate the growth of the prostate gland, leading to prostate enlargement and discomfort. 

Pregnancy

Boldenone undecylenate is contraindicated during pregnancy due to its potential to cause harm to the fetus. Specifically, it can lead to virilization of a female fetus, which involves the development of male physical characteristics. Therefore, it should not be used by women who are pregnant or may become pregnant.

Breastfeeding

The use of boldenone undecylenate is also contraindicated during breastfeeding. There is a risk that the drug could be passed to the infant through breast milk, potentially causing adverse effects. Therefore, women who are breastfeeding should avoid using this medication.

Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain. NOTE: Warming and shaking the vial should redissolve any crystals that may have formed during storage temperatures lower than recommended.